Rescuing Lung Development Through Embryonic Inhibition of Histone Acetylation
Stokes G, Li Z, Talaba N, Genthe W, Brix MB, Pham B, Wienhold MD, Sandok G, Hernan R, Wynn J, Tang H, Tabima DM, Rodgers A, Hacker TA, Chesler NC, Zang P, Murad R, Yuan JX, Shen Y, Chung WK, and McCulley DJ
Science Translational Medicine (2024)

Distensibility, an Early Disease Marker of Pulmonary Vascular Health: Ready for Clinical Application
Raza F and Chesler NC
American Heart Association (2023)

Computational Modeling of Ventricular-Ventricular Interactions Suggest a Role In Clinical Conditions Involving Heart Failure
Kim SM, Randall EB, Jezek F, Beard DA, and Chesler NC
Frontiers (2023)

BME2.1: The Need for a Systems Approach to Addressing Race-Based Disparities in Health and Health Care
Chesler NC and Barabino GA
BME Fronteirs (2023)

You Can’t Spell Shear without “She”: Mechanobiology and Sex Differences in Hypoxic Lung Disease
Caggiano LR and Chesler NC
American Journal of Respiratory Cell and Molecular Biology (2023)

Insights from an AIMBE Workshop: Diversifying Paths to Academic Leadership
Pruitt BL, Chesler NC, Seltzer R, Eniola-Adefeso O, Margulies SS, Campo MS, Simon SI, Grimm MJ, Mandell S, Alleyne A, West JL, and Desai TA
Biomedical Engineering Society (2023)

Estrogen Receptor-α Exerts Endothelium-Protective Effects and Attenuates Pulmonary Hypertension
Frump AL, Yakubov B, Walts A, Fisher A, Cook T, Chesler NC, Lahm T
American Journal of Respiratory Cell and Molecular Biology (2023)

Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy
Rupert C, López JE, Cortez-Toledo E, De la Cruz Cabrera O, Chesler NC, Simpson PC, Campbell SG, and Baker AJ
American Journal of Physiology (2023)

Subject-Specific One-Dimensional Fluid Dynamics Model of Chronic Thromboembolic Pulmonary Hypertension
Kachabi A, Colebank MJ, and Chesler NC
Biomechanics and Modeling in Mechanobiology (2023)

Application and Reduction of a Nonlinear Hyperelastic Wall Model Capturing ex vivo Relationships Between Fluid Pressure, Area, and Wall Thickness in Normal and Hypertensive Murine Left Pulmonary Arteries
Haider MA, Pearce KJ, Chesler NC, Hill NA, and Olufsen MS
International Journal for Numerical Methods in Biomedical Engineering (2023)

Biventricular Interaction During Acute Left Ventricular Ischemia in Mice: A Combined In-Vivo and In-Silico Approach
Colebank MJ, Taylor R, Hacker TA, and Chesler NC
BMES (2023)

Biomechanical and mechanobiological drivers of the transition from postcapillary pulmonary hypertension to combined pre−/postcapillary pulmonary hypertension
Allen BJ, Frye H, Ramanathan R, Caggiano LR, Tabima DM, Chesler NC, Philip JL
Journal of the American Heart Association (2023)

Exercise increases arterial stiffness independent of blood pressure in older veterans
Pewowaruk RJ, Hein AJ, Hansen KM, Barnes JN, Chesler NC, Korcarz CE, Gepner AD
Journal of Hypertension (2023)

An in-silico analysis of experimental designs to study ventricular function: A focus on the right ventricle
Colebank MJ, Chesler NC
PLOS Computational Biology (2023)

Maintaining Inclusion in Engineering in a Post-Dobbs World
Van der Meulen MCH, Wayne JS, Chesler NC and Setton LA
Inside Higher Education - Opinion/Diversity/Career Advice (2022)

Diffuse Myocardial Fibrosis at Cardiac MRI in Young Adults Born Prematurely: A Cross-sectional Cohort Study
François CJ, Barton GP, PhD, Corrado PA, Broman AT, Chesler NC, Eldridge MW, Wieben O, Goss KN
Radiology Cardiothoracic Imaging (2022)

The stronger sex, until menopause: Understanding the impact of estrogen loss on heart function
Conway-O'Donnell CK, Chesler NC
American Journal of Physiology-Heart and Circulatory Physiology (2022)

Multimodality deep phenotyping methods to assess mechanisms of poor right ventricular-pulmonary artery coupling
Raza F, Kozitza C, Lechuga C, Seiter D, Corrado P, Merchant M, Dharmavaram N, Korcarz A, Eldridge M, Francois C, Wieben O, Chesler N
Function (2022)

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest VE/VCO2 and ETCO2 identify pulmonary vascular disease
Raza F, Dharmavaram N, Hess T, Dhingra R, Runo J, Chybowski A, Kozitza C, Batra S, Horn EM, Chesler NC, Eldridge M
Clinical Cardiology (2022)

Sex differences in right ventricular adaptation to pressure overload in a rat model
Cheng TC, Tabima DM, Caggiano LR, Frump AL, Hacker TA, Eickhoff JC, Lahm T, Chesler NC
Journal of Applied Physiology (2022)

Hydrostatic Pressure Controls Angiogenesis Through Endothelial YAP1 During Lung Regeneration
Mammoto T, Hunyenyiwa T, Kyi P et al.
Frontiers in Bioengineering and Biotechnology (2022)

Numerical predictions of shear stress and cyclic stretch in pulmonary hypertension due to left heart failure
Bartolo MA, Gureshi MU, Colebank MJ, Chesler NC, Olufson MS
Biomechanics and Modeling in Mechanobiology (2022)

Development of a PET/MRI exercise stress test for determining cardiac glucose dependence in pulmonary arterial hypertension
Barton GP, Corrado PA, Fracois CJ, Runo JR, Chesler NC, McMillan AB, Wieben O, Goss KN
Pulmonary Circulation (2022)

Pulmonary vascular distensibility with passive leg raise is comparable to exercise and predictive of clinical outcomes in pulmonary hypertension
Kozitza CJ, Dharmavaram N, Tao R, Tamiba DM, Chesler NC, Raza F
Pulmonary Circulation (2022)

Carotid Artery Stiffening With Aging: Structural Versus Load-Dependent Mechanisms in MESA
Pewowaruk RJ, Tedla Y, Korcarz CE , Tattersall MC, Stein JH, Chesler NC, Gepner AD
Circulation (2021)

Non-invasive estimation of pulmonary hemodynamics from 2D-PC MRI with an arterial mechanics method
Pewowaruk RJ, Forouzan O, Raza F, Gepner AD, Chesler NC
Journal of Biomechanics (2021)

Interferon-B-Induced Pulmonary Arterial Hypertension
Raza F, Kozitza C, Chybowski A, Goss KN, Berei T, Runo J, Eldridge M, Chesler NC.
Journals of the American College of Cardiology (2021)

Exaggerated Cardiac Contractile Response to Hypoxia in Adults Born Preterm
Barton GP, Corrado PA, Francois CJ, Chesler NC, Eldridge M, Wieben O, Goss KN.
Journal of Clinical Medicine (2021)

Increased RV:LV Ratio on Chest CT-Angiogram in COVID-19 is a Marker of Adverse Outcomes
Tao R, Burivalova Z, Masri SC, Dharmavaram N, Baber A, Deano R, Hess T, Dhingra R, Runo J, Jarjour N, Vanderpool RR, Chesler N, Kusmirek JE, Eldridge M, Francois C, Raza F.
Research Square (2021)

Dynamic FDG PET Imaging to Probe for Cardiac Metabolic Remodeling in Adults Born Premature
Corrado PA, Barton GP, Razalan-Krause FC, Francois CJ, Chesler NC, Wieben O, Eldridge M, McMillan AB, Goss KN.
Journal of Clinical Medicine (2021)

Citation Diversity Statement in BMES Journals
Rowson B, Duma SM, King MR, Efimov I, Saterbak A, Chesler NC.
Annals of Biomedical Engineering (2021)

17B-Estradiol and estrogen receptor-alpha protect right ventricular function in pulmonary hypertension via BMPR2 and apelin
Frump AL, Albrecht ME, Yakubov B, Breuils-Bonnet S, Nadeau V, Tremblay E, Potus F, Omura J, Cook T, Fisher A, Rodriguez BE, Brown RD, Stenmark KR, Rubinstein CD, Krentz K, Tabima DM, Li R, Sun X, Chesler NC, Provencher S, Bonnet S, Lahm T.
Journal of Clinical Investigation (2021)

Fund Black Scientists
Stevens KR, Masters KS, Imoukhuede PI, Haynes KA, Setton LA, Cosgriff-Hernandez E, Lediju Bell MA, Rangamani P, Sakiyama-Elbert SE, Finley SD, Willits RK, Koppas AN, Chesler NC, Christman KL, Allen JB, Wong JY, El-Samad H, Desa TA, Eniola-Adefeso O.
Cell (2021)

GBT440 Increases Hematocrit and Improves Biventricular Function in Berkeley Sickle Cell Disease Mice
Gassner R, Schreier DA, Hacker TA, Tabima DM, Chesler NC.
Journal of Biomechanical Engineering (2020)

Estrogen Receptor Alpha Prevents Right Ventricular Diastolic Dysfunction and Fibrosis in Female Rats
Cheng TC, Philip JL, Tabima DM, Kumari S, Yakubov B, Frump AL, Hacker TA, Bellofiore A, Li R, Sun X, Goss KN, Lah T, Chesler NC.
American Journal of Physiology – Heart and Circulatory Physiology (2020)

Effects of Red Blood Cell Sickling on Right Ventricular Afterload
Schreier DA, Hacker TA, Tabima DM, Platt MO, Chesler NC.
Experimental Mechanics (2020)

Association Between Preterm Birth and Arrested Cardiac Growth in Adolescents and Young Adults
Goss KN, Haraldsdottir K, Beshish AG, Barton GP, Watson AM, Palta M, Chesler NC, Francois CJ, Wieben O, Eldridge MW.
JAMA Cardiology (2020)

Susceptibility to High-Altitude Pulmonary Edema is Associated with Increased Pulmonary Arterial Stiffness During Exercise
Mulchrone AM, Moulton H, Eldridge MW, Chesler NC.
Journal of Applied Physiology (2019)

Impaired Right Ventricular-Vascular Coupling in Young Adults Born Preterm
Mulchrone AM, Bellofiore A, Douwes JM, Duong N, Beshish AG, Barton GP, Francois CJ, Eldridge MW, Goss KN, Chesler NC.
American Journal of Respiratory and Critical Care Medicine (2019)

Exogenous Estrogen Preserves Distal Pulmonary Arterial Mechanics and Prevents Pulmonary Hypertension in Rats
Philip JL, Tabima DM, Wolf GD, Frump AL, Cheng TC, Schreier DA, Hacker TA, Lahm T, Chesler NC.
American Journal of Respiratory and Critical Care Medicine (2019)

Influence of Image Segmentation on One-Dimensional Fluid Dynamics Predictions in the Mouse Pulmonary Arteries
Colebank MJ, Paun LM, Qureshi MU, Chesler NC, Husmeier D, Olufsen MS, Ellwein LM.
Journal of the Royal Society Interface (In Press) (2019)

Exercise-Induced Changes in Pulmonary Arterial Stiffness in Pulmonary Hypertension
Fourozan O, Dinges E, Runo JR, Keevil JG, Eickhoff JC, Francois C, Chesler NC.
Frontiers in Physiology (2019)

Pulmonary Vascular Mechanical Consequences of Ischemic Heart Failure and Implications for Right Ventricular Function
Philip JL, Murphy TM, Schreier DA, Stevens S, Tabima DM, Albrecht M, Frump AL, Hacker TA, Lahm T, Chesler NC.
American Journal of Physiology – Heart and Circulatory Physiology (2019)

Beneficial Effects of Mesenchymal Stem Cell Delivery via a Novel Cardiac Bioscaffold on Right Ventricles of Pulmonary Arterial Hypertensive Rats.
Schmuck EG, Hacker TA, Schreier DA, Chesler NC, Wang Z.
American Journal of Physiology – Heart and Circulatory Physiology (2019)

A Large Animal Model of Right Ventricular Failure due to Chronic Thromboembolic Pulmonary Hypertension: A Focus on Function
Mulchrone AM, Kellihan HB, Forouzan O, Hacker TA, Bates ML, Francois CJ, Chesler NC.
Frontiers in Cardiovascular Medicine (2019)

A How-To Guide for Promoting Diversity and Inclusion in Biomedical Engineering
Naomi C. Chesler
Annals of Biomedical Engineering (2019)

MRI assessment of aortic flow in patients with pulmonary arterial hypertension in response to exercise
Macdonald JA, Francois CJ, Forouzan O, Chesler NC, Wieben O.
BMC Medial Imaging (2018)

Hemodynamic assessment of pulmonary hypertension in mice: A model based analysis of the disease mechanism
Qureshi MU, Colebank MJ, Paun LM, Ellwein Fix L, Chesler NC, Haider MA, Hill NA, Husmeier D, Olufsen MS.
Biomechanics and modeling in mechanobiology (2018)

Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward
Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM.
American Journal of Respiratory and Critical Care Medicine (2018)

Know your limitations: assumptions in the single beat method for estimating right ventricular pulmonary vascular coupling
Philip JL, Chesler NC.
American Journal of Respiratory and Critical Care Medicine (2018)

Multi-scale Structure-Function Relationships in Right Ventricular Failure Due to Pressure Overload
Cheng TC, Philip JL, Tabima DM, Hacker TA, Chesler NC.
American Journal of Physiology-Heart and Circulatory Physiology (2018)

Early Pulmonary Vascular Disease in Young Adults Born Preterm
Goss KN, Beshish AG, Barton GP, Haraldsdottir K, Levin TS, Tetri LH, Battiola TJ, Mulchrone AM, Pegelow DF, Palta M, Lamers LJ, Watson AM, Chesler NC, Eldridge MW.
American Journal of Respiratory and Critical Care Medicine (2018)

Impaired myofilament contraction drives right ventricular failure secondary to pressure overload: model simulations, experimental validation, and treatment predictions
Philip JL, Pewowaruk RJ, Chen CS, Tabima DM, Beard D, Baker AJ, Chesler NC.
Frontiers in Physiology (2018)

Cardiovascular function and structure are preserved despite induced ablation of BMP1-related proteinases
Golob MJ, Massoudi D, Tabima DM, Johnston JL, Wolf GD, Hacker TA, Greenspan DS, Chesler NC.
Cellular and Molecular Bioengineering (2018)

Multiscale Computational Analysis of RV Mechanoenergetics
Pewowaruk RJ, Philip JL, Tewari SG, Chen CS, Nyaeme MS, Wang Z, Tabima DM, Baker AJ, Beard DA, Chesler NC.
Journal of Biomechanical Engineering (2018)

Organ-level right ventricular dysfunction with preserved Frank-Starling mechanism in a mouse model of pulmonary arterial hypertension
Wang Z, Patel JR, Schreier DA, Hacker TA, Moss RL, Chesler NC.
Journal of Applied Physiology (2018)

Influence of End Customer Exposure on Product Design Within an Epistemic Game Environment
Markovetz M, Sullivan S, Clark R, Swiecki Z, Arastoopour Irgens G, Chesler NC, Shaffer DW, Bodnar CA.
Advances in Engineering Education, 2017 (2017)

Data-Enabled Cognitive Modeling: Validating student engineers’ fuzzy design-based decision-making in a virtual design problem
Arastoopour Irgens G, Chesler NC, Linderoth J, Shaffer DW.
Computer Applications in Engineering Education, 2017 (2017)

PBX transcription factors drive pulmonary vascular adaptation to birth
McCulley DJ, Wienhold MD, Hines EA, Hacker TA, Rogers A, Pewowaruk RJ, Zewdu R, Chesler NC, Selleri L, Sun X.
The Journal of Clinical Investigation (2017)

Characteristic Impedance: Frequency or Time Domain Approach.
Qureshi MU, Colebank M, Schreier D, Tabima DM, Haider MA, Chesler NC, Olufsen MS.
Physiological Measurement (2017)

A novel single-beat approach to assess right ventricular systolic function.
Bellofiore A, Vanderpool RR, Brewis MJ, Peacock AJ, Chesler NC.
Journal of Applied Physiology (2017)

Right ventricular-pulmonary vascular interactions: A Review
Tabima DM, Philip J, Chesler NC.
Physiology (2017)

Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival.
Blyth KG, Bellofiore A, Jayasekera G, Foster JE, Steedman T, Chesler NC, Peacock AJ.
Pulmonary Circulation Journal (2017)

Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension.
Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC.
Physiology Reports (2017)

Pulmonary arterial strain- and remodeling-induced stiffening are differentiated in a chronic model of pulmonary hypertension.
Golob MJ, Tabima DM, Wolf GD, Johnston JL, Forouzan O, Mulchrone AM, Kellihan HB, Bates ML, Chesler NC.
Journal of Biomechanics (2017)

Pulmonary vascular collagen content, not cross-linking, contributes to right ventricular pulsatile afterload and overload in early pulmonary hypertension.
Wang Z, Schreier DA, Abid H, Hacker TA, Chesler NC.
Journal of Applied Physiology (2017)

Reduced haemodynamic coupling and exercise are associated with vascular stiffening in pulmonary arterial hypertension.
Bellofiore A, Dinges E, Naeije R, Mkrdichian H, Beussink-Nelson L, Bailey M, Cuttica MJ, Sweis R, Runo JR, Keevil JG, Francois CJ, Shah SJ, Chesler NC.
Heart (2017)

A Grounded Qualitative Analysis of the Effect of a Focus Group on Design Process in a Virtual Internship
Markovetz M, Sullivan S, Clark R, Swiecki Z, Arastoopour Irgens G, Chesler NC, Shaffer DW, Bodnar CA.
International Journal of Engineering Education, 2017 (2017)

Estrogen preserves pulsatile pulmonary arterial hemodynamics in pulmonary arterial hypertension.
Liu A, Hacker T, Eickhoff JC, Chesler NC.
Annals of Biomedical Engineering (2017)

17?-estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension.
Lahm T, Frump AL, Albrecht ME, Fisher AJ, Cook TG, Jones TJ, Yakubov B, Whitson J, Fuchs RK, Liu A, Chesler NC, Brown MB.
American Journal of Physiology-Lung Cellular and Molecular Physiology (2016)

Heterogeneous mechanics of the mouse pulmonary arterial network.
Lee P, Carlson BE, Chesler NC, Olufsen MS, Qureshi UM, Smith NP, Sochi T, Beard DA.
Biomechanics and Modeling in Mechanobiology (2016)

Imaging right ventricular function to predict outcome in pulmonary arterial hypertension.
Brewis MJ, Bellofiore A, Vanderpool RR, Chesler NC, Johnson MK, Naeije R, Peacock AJ.
International Journal of Cardiology (2016)

Limiting collagen turnover via collagenase-resistance attenuates right ventricular dysfunction and fibrosis in pulmonary arterial hypertension.
Golob MJ, Wang Z, Prostrollo AJ, Hacker TA, Chesler NC.
Physiological Reports (2016)

Magnetic resonance and computed tomography imaging for the evaluation of pulmonary hypertension.
Freed B, Collins J, Francois C, Barker A, Cuttica M, Chesler NC, Markl M, Shah S.
JACC Cardiovascular Imaging (2016)

Teaching and Assessing Engineering Design Thinking with Virtual Internships and Epistemic Network Analysis
Arastoopour G, Shaffer DW, Swiecki Z, Ruis JR, Chesler NC.
International Journal of Engineering Education, 2015 (2015)

Increased red blood cell stiffness increases pulmonary vascular resistance and pulmonary arterial pressure.
Schreier DA, Forouzan O, Hacker TA, Sheehan J, Chesler NC.
Journal of Biomechanical Engineering (2015)

Non-invasive measurement using cardiovascular magnetic resonance of changes in pulmonary artery stiffness with exercise.
Forouzan O, Warczytowa J, Wieben O, François CJ, Chesler NC.
Journal of Cardiovascular Magnetic Resonance (2015)

Validation of an arterial constitutive model accounting for collagen content and crosslinking.
Tian L, Wang Z, Liu Y, Eickhoff JC, Eliceiri KW, Chesler NC.
Acta Biomaterialia (2015)

17?-estradiol attenuates conduit pulmonary artery mechanical property changes with pulmonary arterial hypertension.
Liu A, Tian L, Golob M, Eickhoff JC, Boston M, Chesler NC.
Hypertension (2015)

What does the time constant of the pulmonary circulation tell us about the progression of right ventricular dysfunction in pulmonary arterial hypertension?
Bellofiore A, Wang Z, Chesler NC.
Pulmonary Circulation (2015)

Stretch calculated from grip distance accurately approximates mid-specimen stretch in large elastic arteries in uniaxial tensile tests.
Tian L, Henningsen J, Salick MR, Crone WC, Gunderson M, Dailey SH, Chesler NC.
Journal of the Mechanical Behavior of Biomedical Materials (2015)

Accuracy of doppler echocardiographic estimates of pulmonary artery pressures in a canine model of pulmonary hypertension.
Soydan LC, Kellihan HB, Bates ML, Stepien RL, Consigny DW, Bellofiore A, Francois CJ, Chesler NC.
Journal of Veterinary Cardiology (2015)

A novel in vivo approach to assess radial and axial distensibility of large and intermediate pulmonary artery branches.
Bellofiore A, Henningsen J, Lepak CG, Tian L, Roldan-Alzate A, Kellihan HB, Consigny DW, Francois CJ, Chesler NC.
Journal of Biomechanical Engineering (2015)

Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function.
Golob MJ, Tian L, Wang Z, Zimmerman TA, Caneba CA, Hacker TA, Song G, Chesler NC.
Journal of Biomechanical Engineering (2015)

A Novel Paradigm for Engineering Education: Virtual Internships With Individualized Mentoring and Assessment of Engineering Thinking
Chesler NC, Ruis AR, Collier W, Swiecki Z, Arastoopour G, Shaffer DW.
Journal of Biomechanical Engineering, 2014 (2014)

Epistemic Persistence: A Simulation-based Approach to Increasing Participation of Women in Engineering
Arastoopour G, Chesler NC, Shaffer DW.
Journal of Women and Minorities in Science and Engineering, 2014 (2014)

Impact of hematocrit on right ventricular afterload during the progression of hypoxic pulmonary hypertension.
Schreier DA, Hacker T, Hunter KS, Eickoff J, Liu A, Song G, Chesler NC.
Journal of Applied Physiology (2014)

Pulmonary artery relative area change is inversely related to ex vivo measured arterial elastic modulus in the canine model of acute pulmonary embolization.
Tian L, Kellihan HB, Henningsen J, Bellfiore A, Forouzan O, Roldan-Alzate A, Consigny DW, Gunderson M, Dailey SH, Francois CJ, Chesler NC.
Journal of Biomechanical Engineering (2014)

Cardiac tissue structure, properties, and performance: A materials science perspective.
Golob M, Moss RL, Chesler NC.
Annals of Biomedical Engineering (2014)

4D flow assessment of pulmonary artery flow and wall shear stress in adult pulmonary arterial hypertension: Results from two institutions.
Barker AJ, Roldan-Alzate A, Entezari P, Shah SJ, Chesler NC, Wieben O, Markl M, Francois CJ.
Magnetic Resonance in Medicine (2014)

Direct and Indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension.
Liu A, Schreier D, Lian T, Eickhoff JC, Wang Z, Hacker T, Chesler NC.
American Journal of Physiology – Heart and Circulatory Physiology (2014)

Low cost MRI-compatible stepper exercise device for use cardiac stress tests.
Forouzan O, Flink E, Warczytowa J, Thate N, Hanske A, Lee T, Roldan-Alzate A, Francois C, Wieben O, Chesler NC.
Journal of Medical Devices (2014)

Non-invasive assessment of cardiac function and pulmonary vascular resistance in an canine model of acute thromboembolic pulmonary hypertension using 4D flow cardiovascular magnetic resonance.
Roldan-Alzate A, Frydrychowicz A, Johnson KM, Kellihan H, Chesler NC, Wieben O, Francois CJ.
Journal of Cardiovascular Magnetic Resonance (2014)

Development of Concept-based Physiology Lessons for Biomedical Engineering Undergraduate Students
Nelson RK, Chesler NC, Strang KT.
Advances in Physiology Education, 2013 (2013)

Progressive right ventricular function and structural changes in a mouse model of pulmonary arterial hypertension.
Wang Z, Schreier DA, Hacker T, Chesler NC.
Physiology Reports (2013)

Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice.
Tewari SG, Bugenhagen SM, Wang Z, Schreier DA, Carlson BE, Chesler NC, Beard DA.
Frontiers in Physiology (2013)

Changes in large pulmonary arterial viscoelasticity in chronic pulmonary hypertension.
Wang Z, Lakes RS, Golob M, Eickhoff JC, Chesler NC.
PLoS One (2013)

4D flow-sensitive MR estimation of pulmonary vascular resistance.
Roldan-Alzate A, Francois C, Wieben O, Chesler NC, Frydrychowicz A.
Journal of Cardiovascular Magnetic Resonance (2013)

Pulmonary vascular mechanics: important contributors to the increased right ventricular afterload of pulmonary hypertension.
Wang Z, Chesler NC.
Experimental Physiology (2013)

Comparison of approaches to quantify arterial damping capacity from pressurization tests on mouse conduit arteries.
Tian L, Wang Z, Lakes RS, Chesler NC.
Journal of Biomechanical Engineering (2013)

Magnetic resonance and computed tomography imaging of the structural and functional changes of pulmonary arterial hypertension.
Shiebler ML, Bhalla S, Runo J, Jarjour N, Roldan A, Chesler NC, Francois CJ.
Journal of Thoracic Imaging (2013)

The role of collagen synthesis in ventricular and vascular adaptation to hypoxic pulmonary hypertension.
Schreier DA, Hacker T, Song G, Chesler NC.
Journal of Biomechanical Engineering (2013)

Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature.
Bellofiore A, Chesler NC.
Annals of Biomedical Engineering (2013)

Blood pressure, artery size, and artery compliance parallel bone size and strength in mice with differing ece1 expression.
Wang Z, Kristianto J, Ooi CY, Johnson MG, Litscher SJ, Pugh T, Sandhu G, Chesler NC, Blank RD.
Journal of Biomechanical Engineering (2013)

Effects of collagen deposition on passive and active mechanical properties of large pulmonary arteries in hypoxic pulmonary hypertension.
Wang Z, Lakes RS, Eickhoff JC, Chesler NC.
Biomechanics and Modeling in Mechanobiology (2013)

Design of a Professional Practice Simulator for Educating and Motivating First-Year Engineering Students
Chesler NC, Arastoopour G, D’Angelo CM, Bagley EA, Shaffer DW.
Advances in Engineering Education, 2012 (2012)

Exercise stress echocardiography of the pulmonary circulation: limits of normal and sex differences.
Argiento P, Vanderpool RR, Mule M, Russo MG, D’Alto M, Bossone E, Chesler NC, Naeije R.
Chest (2012)

Impact of acute pulmonary embolization on arterial stiffening and right ventricular function in dogs.
Bellofiore A, Roldán-Alzate A, Besse M, Kellihan HB, Consigny DW, Francois CJ, Chesler NC.
Annals of Biomedical Engineering (2012)

In vivo and in vitro measurements of pulmonary arterial stiffness: A brief review.
Tian L, Chesler NC.
Pulmonary Circulation (2012)

Role of collagen content and cross-linking in large pulmonary arterial stiffening after chronic hypoxia.
Wang Z, Chesler NC.
Biomechanics and Modeling in Mechanobiology (2012)

Patchy deletion of Bmpr1a potentiates proximal pulmonary artery remodeling in mice exposed to chronic hypoxia.
Vanderpool RR, El-Bizri N, Rabinovitch M, Chesler NC.
Biomechanics and Modeling in Mechanobiology (2012)

Persistent vascular collagen accumulation alters hemodynamic recovery from chronic hypoxia.
Tabima D, Roldan-Alzate A, Wang Z, Hacker T, Molthen R, Chesler NC.
Journal of Biomechanics (2012)

Pulmonary circulation at exercise.
Naeije R, Chesler NC.
Comprehensive Physiology (2012)

Pulmonary vascular wall stiffness: An important contributor to increased right ventricular afterload in pulmonary hypertension.
Wang Z, Chesler NC.
Pulmonary Circulation (2011)

Characterization of the isolated, ventilated and instrumented mouse lung perfused with pulsatile flow.
Vanderpool RR, Chesler NC.
Journal of Visualized Experiments (2011)

Effects of acute rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function.
Vanderpool RR, Kim AR, Molthen R, Chesler NC.
Journal of Applied Physiology (2011)

The Pipeline Still Leaks and More Than You Think: A Status Report on Gender Diversity in Biomedical Engineering
Chesler NC, Barabino G, Bhatia SN, Richards-Kortum R.
Annals of Biomedical Engineering, 2010 (2010)

Measuring right ventricular function in the normal and hypertensive mouse hearts using admittance-derived pressure-volume loops.
Tabima DM, Hacker TA, Chesler NC.
American Journal of Physiology – Heart and Circulatory Physiology (2010)

The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension.
Ooi CY, Wang Z, Tabima DM, Eickhoff JC, Chesler NC.
American Journal of Physiology – Heart and Circulatory Physiology (2010)

The effects of vaso activity and hypoxic pulmonary hypertensionon extralobar pulmonary artery biomechanics.
Tabima DM, Chesler NC.
Journal of Biomechanics (2010)

Time course of intermittent hypoxia-induced impairments in resistance artery structure and function.
Philippi N, Bird C, Marcus N, Olson E, Chesler NC, Morgan B.
Respiratory Physiology & Neurobiology (2010)

Impedance in isolated mouse lungs for the determination of site of action of vasoactive agents and disease.
Vanderpool RR, Naeije R, Chesler NC.
Annals of Biomedical Engineering (2010)

Shear stress regulation of nitric oxide production in uterine and placental artery endothelial cells: experimental studies and hemodynamic models of shear stress forces on endothelial cells
Sprague BJ, Chesler NC, Magness RR.
International Journal of Developmental Biology (2010)

Human Respiratory Mechanics Demonstration Model
Anderson J, Goplen C, Murray L, Seashore K, Soundarrajan M, Lokuta A, Strang K, Chesler NC.
Advances in Physiology Education, 2009 (2009)

How to Measure Pulmonary Vascular and Right Ventricular Function
Chesler NC, Roldan A, Vanderpool RR, Naeije R.
Conf Proc IEEE Eng Med Biol Soc (2009)

Exercise stress echocardiography for the study of the pulmonary circulation.
Argiento P, Chesler NC, Mulè M, D’Alto M, Bossone E, Unger P, Naeije R.
European Respiratory Journal (2009)

Characterization of CSF hydrodynamics in the presence and absence of tonsilar ectopia by means of computational flow analysis.
Roldan A, Haughton VM, Wieben O, Osswald T, Chesler NC.
American Journal of Neuroradiology (2009)

Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia
Estrada KD, Chesler NC.
Biomechanics and Modeling in Mechanobiology (2009)

The effects of the ovarian cycle and pregnancy on uterinevascular impedance and uterine artery mechanics.
Sprague BJ, Phernetton TM, Magness RR, Chesler NC.
European Journal of Obstetrics and Gynecology and Reproductive Biology (2009)

Transmission line models to simulate the impedance of the uterine vasculature during the ovarian cycle and pregnancy.
Zhu Y, Sprague BJ, Phernetton TM, Magness RR, Chesler NC.
European Journal of Obstetrics and Gynecology and Reproductive Biology (2009)

Chronic hypoxia-induced pulmonary hypertension does lead to loss of pulmonary vasculature.
Rabinovitch M, Chesler NC, Molthen RC.
Journal of Applied Physiology (2007)

Pulmonary vascular remodeling in isolated mouse lungs: Effects on pulsatile pressure–flow relationships.
Tuchscherer HA, Vanderpool RR, Chesler NC.
Journal of Biomechanics (2007)

The mechanobiology of pulmonary vascular remodeling in the congenital absence of eNOS.
Kobs RW, Chesler NC.
Biomechanics and Modeling in Mechanobiology (2006)

Pulmonary vascular resistance and impedance in isolated mouse lungs: Effects of pulmonary emboli.
Tuchscherer HA, Webster E and Chesler NC
Annals of Biomedical Engineering (2006)

A method for dynamic system characterization using hydraulic series resistance.
Kim D, Chesler NC, Beebe DJ.
Lab on a Chip (2006)

Theater as a Community-building Strategy for Women in Engineering: Theory and Practice
Chesler NC, Chesler MA.
Journal of Women and Minorities in Science and Engineering, 2005 (2005)

Pressure-induced vector transport in human saphenous vein
*Ander S, *MacLennan M, Bentil S, Leavitt B, Chesler NC.
Annals of Biomedical Engineering (2005)

Linked Mechanical and biological aspects of pulmonary vascular remodeling with hypoxia-induced hypertension in mice.
Kobs RW, Eickhoff JE, Muvarak NE, Chesler, NC.
American Journal of Physiology: Heart & Circulatory Physiology (2005)

Measurements of mouse pulmonary artery biomechanics.
Chesler NC, Thompson-Figueroa J, Millburne K.
Journal of Biomechanical Engineering (2004)

Mechanical properties of rat middle cerebral arteries with and without myogenic tone.
Coulson R, Cipolla MJ, Vitullo L and Chesler NC.
Journal of Biomechanical Engineering (2004)

On Belay: Peer-mentoring and Adventure Education for Women Faculty in Engineering
Chesler NC, Single PB, Mikic B.
Journal of Engineering Education, 2003 (2003)

Hypoxia-induced changes in the mechanical properties of the mouse pulmonary artery.
Kobs RW, Muvarak NE, Chesler NC.
ASME M.S. Paper Competition (2003)

Particle deposition in arteries ex vivo: Effects of pressure, flow and waveform.
Chesler NC, Enyinna OC.
Journal of Biomechanical Engineering (2003)

Gender-informed Mentoring Strategies for Women in Engineering: On Establishing a Caring Community
Chesler NC, Chesler MA.
Journal of Engineering Education, 2002 (2002)

Effects of ischemia and myogenic reactivity on the active and passive mechanical properties of rat cerebral arteries.
Coulson R, Chesler NC, Vitullo L, Cipolla MJ.
American Journal of Physiology – Heart & Circulatory Physiology (2002)

Early effects of arterial hemodynamic conditions on human saphenous vein perfused ex vivo.
Mavromatis K, Fukai T, Tate M, Chesler NC, Ku D, Galis ZS.
Arteriosclerosis, Thrombosis and Vascular Biology (2000)

Transmural pressure induces matrix-degrading activity in porcine arteries ex vivo.
Chesler NC, Ku DN, Galis ZS.
American Journal of Physiology (1999)

Simplified ex vivo culture techniques for porcine arteries.
Chesler NC, Conklin BS, Han HC, Ku DN.
Journal of Vascular Investigation (1998)

Performance analysis of a cardiac assist device in counterpulsation.
Chesler NC, Kamm RD.
Journal of Biomechanical Engineering (1998)

Surface EMG as a fatigue indicator during FES-aided standing.
Chesler NC, Durfee W.
Journal of Electrophysiology and Kinesiology (1997)